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[Alteration of Th17 cells, immunoglobins and complements levels in peripheral blood of patients with refractory recurrent aphthous ulcer]
- Source :
- Shanghai kou qiang yi xue = Shanghai journal of stomatology. 26(5)
- Publication Year :
- 2018
-
Abstract
- To observe the levels of Th17 cells, immunoglobins and complements in peripheral blood of patients with refractory recurrent aphthous ulcer (refractory RAU) patients.Totally, 30 patients with refractory RAU and 21 healthy controls were enrolled into this study. Flow cytometry was performed to determine the frequency of Th17 cells in the peripheral blood. Immune scatter turbidimetry was adopted to measure the levels of IgA, IgG, IgM, IgE, C3 and C4 in the peripheral blood. Meanwhile, the correlations between the frequency of Th17 cells and the levels of immunoglobins or complements were analyzed. SPSS17.0 software package was used to analyze the date.Compared with the control group, the percentage of Th17 cells (CD3The levels of Th17 cells, immunoglobins and complements in refractory RAU patients are significantly different from healthy human, which may play an important role in the pathogenesis of refractory RAU. There may be some relationship between Th17 cells and the change of humoral immunity in refractory RAU.
- Subjects :
- Humans
Immunoglobulins
Th17 Cells
Stomatitis, Aphthous
Flow Cytometry
Subjects
Details
- ISSN :
- 10067248
- Volume :
- 26
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Shanghai kou qiang yi xue = Shanghai journal of stomatology
- Accession number :
- edsair.pmid..........74923ac653b51c4b0a2a2898cc06d68a