Discovery of structurally distinct tricyclic M

Authors :: Kayla J, Temple
Madeline F, Long
Julie L, Engers
Katherine J, Watson
Sichen, Chang
Vincent B, Luscombe
Alice L, Rodriguez
Colleen M, Niswender
Thomas M, Bridges
P Jeffrey, Conn
Darren W, Engers
Craig W, Lindsley
Source :: Bioorganicmedicinal chemistry letters. 30(4)
Publication Year :: 2019
Abstract: This Letter details our efforts to develop new M

Subjects :: Pyridazines
Inhibitory Concentration 50
Structure-Activity Relationship
Allosteric Regulation
Receptor, Muscarinic M4
Drug Design
Quinazolines
Animals
Humans
Triazoles
Half-Life
Rats

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