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[Cardiac Metastasis in a Patient with Clear Cell Renal Cell Carcinoma who Underwent Multimodality Therapy for Multiple Metastases after Radical Nephrectomy]

Authors :
Shinichi, Takeuchi
Kosuke, Mizutani
Koji, Iinuma
Yuka, Muramatsu-Maekawa
Kengo, Horie
Taku, Kato
Keita, Nakane
Tomohiro, Tsuchiya
Masahiro, Nakano
Takuya, Koie
Source :
Hinyokika kiyo. Acta urologica Japonica. 65(6)
Publication Year :
2019

Abstract

The patient underwent laparoscopic left radical nephrectomy for clear cell renal cell carcinoma (ccRCC). After surgery, the patient had multiple lung metastases and underwent the combination therapy of radiofrequency ablation, interferon-alpha, and inteleukin-2. Thereafter, computed tomography showed multiple lymph node and brain metastases. The patient was administered targeted therapy and radiation. Eventually, the patient suddenly complained of dyspnea. An echocardiogram, coronary angiography and magnetic resonance imaging suggested acute heart failure and pericardial effusion due to a metastatic tumor in the cardiac anteroseptal and posterior wall. Nivolumab was administered for cardiac metastases. The patient has been in stable condition with no progression of cardiac metastases after the administration of nivolumab for 22 months.

Details

ISSN :
00181994
Volume :
65
Issue :
6
Database :
OpenAIRE
Journal :
Hinyokika kiyo. Acta urologica Japonica
Accession number :
edsair.pmid..........7293714dca454fc642f045cd8df5e4da