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[Specific chromosome aberrations in 3 patients with Burkitt-like leukemia (Fab: L3)]

Authors :
H, Nowotny
D, Lutz
O, Krieger
M, Lambrou
P, Bettelheim
Source :
Wiener klinische Wochenschrift. 97(3)
Publication Year :
1985

Abstract

Karyotype analysis using the Tri-staining-technique (Chromomycin A3/Distamycin A/DAPI) and subsequent DAPI/AMD staining (Schweizer, 1981) was performed on the bone marrow and peripheral blood of three patients with "Burkitt-like" acute lymphatic leukaemia (FAB: L3). In two patients we found the specific translocation t(8;22). One patient displayed in addition a structural abnormality of chromosome 9, visualized with C-banding using the DA/DAPI stain, and in two patients we found specific abnormalities of chromosome 1. Several patterns of the abnormal chromosome 1 revealed an intercalated DA/DAPI positive C-band in the elongated long arm.

Details

Language :
German
ISSN :
00435325
Volume :
97
Issue :
3
Database :
OpenAIRE
Journal :
Wiener klinische Wochenschrift
Accession number :
edsair.pmid..........70767be446ed7359cf33b49cdb0af7a6