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Putative Synthetic Cannabinoids MEPIRAPIM, 5F-BEPIRAPIM (NNL-2), and Their Analogues Are T-Type Calcium Channel (Ca

Authors :
Richard C, Kevin
Somayeh, Mirlohi
Jamie J, Manning
Rochelle, Boyd
Elizabeth A, Cairns
Adam, Ametovski
Felcia, Lai
Jia Lin, Luo
William, Jorgensen
Ross, Ellison
Roy R, Gerona
David E, Hibbs
Iain S, McGregor
Michelle, Glass
Mark, Connor
Chris, Bladen
Gerald W, Zamponi
Samuel D, Banister
Source :
ACS chemical neuroscience. 13(9)
Publication Year :
2022

Abstract

Synthetic cannabinoid receptor agonists (SCRAs) are a large and growing class of new psychoactive substances (NPSs). Two recently identified compounds, MEPIRAPIM and 5F-BEPIRAPIM (NNL-2), have not been confirmed as agonists of either cannabinoid receptor subtype but share structural similarities with both SCRAs and a class of T-type calcium channel (Ca

Details

ISSN :
19487193
Volume :
13
Issue :
9
Database :
OpenAIRE
Journal :
ACS chemical neuroscience
Accession number :
edsair.pmid..........6f2d2b02409f121e5d20f6fd0ab7bb36