Amelioration of cognitive impairments induced by GABA hypofunction in the male rat prefrontal cortex by direct and indirect dopamine D

Authors :: Meagan L, Auger
Juliet, Meccia
Anthony G, Phillips
Stan B, Floresco
Source :: Neuropharmacology. 162
Publication Year :: 2019
Abstract: Deficits in prefrontal cortex (PFC) GABAergic neurotransmission are linked to cognitive impairments seen in schizophrenia and other disorders, and pharmacological reduction of PFC GABA

Subjects :: Male
Receptors, Dopamine D1
Berberine Alkaloids
Prefrontal Cortex
Benzazepines
Bicuculline
Synaptic Transmission
Rats
Cognition
Memory, Short-Term
Dopamine Agonists
Animals
Conditioning, Operant
Cognitive Dysfunction
GABA-A Receptor Antagonists
Maze Learning
gamma-Aminobutyric Acid

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