GMP-Compliant Manufacturing of TRUCKs: CAR T Cells targeting GD

Authors :: Wolfgang, Glienke
Anna Christina, Dragon
Katharina, Zimmermann
Alexandra, Martyniszyn-Eiben
Mira, Mertens
Hinrich, Abken
Claudia, Rossig
Bianca, Altvater
Krasimira, Aleksandrova
Lubomir, Arseniev
Christina, Kloth
Andriana, Stamopoulou
Thomas, Moritz
Holger N, Lode
Nikolai, Siebert
Rainer, Blasczyk
Lilia, Goudeva
Axel, Schambach
Ulrike, Köhl
Britta, Eiz-Vesper
Ruth, Esser
Source :: Frontiers in immunology. 13
Publication Year :: 2021
Abstract: Chimeric antigen receptor (CAR)-engineered T cells can be highly effective in the treatment of hematological malignancies, but mostly fail in the treatment of solid tumors. Thus, approaches using 4

Subjects :: Killer Cells, Natural
Motor Vehicles
Interleukin-18
Cytokines
CD8-Positive T-Lymphocytes

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