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A new cross-over region for hemogloboin-Lepore-Hollandia

Authors :
Vivian, Chan
Patrick, Au
Ben, Yip
Tai-Kwong, Chan
Source :
Haematologica. 89(5)
Publication Year :
2004

Abstract

Hb Lepore-Hollandia, identified in a Thai patient, was found to be due to a new cross-over between IVS1-nt 42 and nt 56 of the delta- and beta-globin genes. This differs from a previous case which crossed-over between codon 22 and IVS1-nt 16. Two independent homologous unequal cross-over events account for these two Lepore-Hollandia genes.

Details

ISSN :
15928721
Volume :
89
Issue :
5
Database :
OpenAIRE
Journal :
Haematologica
Accession number :
edsair.pmid..........6c7f5038295edf5cf565e36df1462cb1