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Better preservation of cognitive faculty in continuous ambulatory peritoneal dialysis
- Source :
- Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis. 13
- Publication Year :
- 1993
-
Abstract
- We employed the so-called event-correlated potential (ECP) P300, a neurophysiological test which explores the circuits of attention and memory in the brain and is altered in subjects with a dismetabolic or degenerative encephalopathy, in order to evaluate the cognitive faculty in two groups of uremic patients [18 on continuous ambulatory peritoneal dialysis (CAPD), 15 on hemodialysis (HD)] comparable with respect to age and time on dialysis. The values of latency (msec) of P300 resulted in CAPD patients 356 +/- 26 in CZ (central zero electrodes) and 357.5 +/- 25 in PZ (parietal zero electrodes), not significantly different from the values in normal controls (341 +/- 14.5 in CZ and 340 +/- 15.6 in PZ) and in HD patients postdialysis (354 +/- 24.4 in CZ and 354 +/- 25.6 in PZ). On the contrary, the predialytic values of HD patients (384 +/- 25.6 CZ and 385 +/- 25.5 in PZ) were significantly different from the postdialytic values and from the values of CAPD patients and controls (p0.01). These results support the conclusion that HD is able to restore a normal cognitive faculty only transiently in the postdialytic phase, while CAPD maintains this important function steadily close to the normal range, thus being clearly better than HD.
Details
- ISSN :
- 08968608
- Volume :
- 13
- Database :
- OpenAIRE
- Journal :
- Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis
- Accession number :
- edsair.pmid..........6bea0bc308b2e621a7b4411114eb8596