Back to Search
Start Over
[Severe microcytic anemia with megaloblastic changes in the bone marrow. A hematological paradoxon?]
- Source :
- Der Internist. 50(7)
- Publication Year :
- 2009
-
Abstract
- We discuss the case of a 32 year-old male with severe microcytic anemia (hemoglobin 2,9 g/dl) and megaloblastic changes in the bone marrow. The patient reported of substantial dietary weight loss. The family history was positive for beta-thalassemia. Previous blood work showed iron deficiency with mild anemia. Further work-up verified beta-thalassemia minor and revealed severely decreased vitamin B12 levels with positive anti intrinsic-factor antibodies, pathognomonic for autoimmune pernicious anemia. The paradoxon therefore dissolved as a pernicious anemia with megaloblastic changes with microcytic erythrocytes due to beta-thalassemia.
Details
- Language :
- German
- ISSN :
- 14321289
- Volume :
- 50
- Issue :
- 7
- Database :
- OpenAIRE
- Journal :
- Der Internist
- Accession number :
- edsair.pmid..........6b30ce2a2b849206c89dddd4e5133887