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Manipulation of the Global Regulator

Authors :
Bo, Yuan
Nancy P, Keller
Berl R, Oakley
Jason E, Stajich
Clay C C, Wang
Source :
ACS chemical biology. 17(10)
Publication Year :
2023

Abstract

Genome sequencing of filamentous fungi has demonstrated that most secondary metabolite biosynthetic gene clusters (BGCs) are silent under standard laboratory conditions. In this work, we have established an in vitro CRISPR-Cas9 system in

Details

ISSN :
15548937
Volume :
17
Issue :
10
Database :
OpenAIRE
Journal :
ACS chemical biology
Accession number :
edsair.pmid..........643cf52720bd40fbfa9cd60adebb125f