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A pharmacogenomic analysis using L1000CDS
- Source :
- Cancer letters. 465
- Publication Year :
- 2019
-
Abstract
- Pancreatic cancer is one of the leading causes of cancer death, mainly due to the absence of early diagnostic tool and effective therapeutic agents. To identify an effective therapeutic agent for pancreatic ductal adenocarcinoma cells (PDAC), we used 10 Gene Expression Omnibus (GEO) data sets and L1000CDS
- Subjects :
- Male
Glycogen Synthase Kinase 3 beta
Cell Survival
Pyridones
TOR Serine-Threonine Kinases
Pyrimidinones
Thiophenes
Xenograft Model Antitumor Assays
Pharmacogenomic Testing
Gene Expression Regulation, Neoplastic
Pancreatic Neoplasms
Inhibitory Concentration 50
Mice
Pyrimidines
Cell Movement
Cell Line, Tumor
Antineoplastic Combined Chemotherapy Protocols
Animals
Humans
Carcinoma, Pancreatic Ductal
Cell Proliferation
Signal Transduction
Subjects
Details
- ISSN :
- 18727980
- Volume :
- 465
- Database :
- OpenAIRE
- Journal :
- Cancer letters
- Accession number :
- edsair.pmid..........6351f0a4702381f61e9f5ec94ba05704