Back to Search Start Over

[Effect of Different Hemapheresis Procedures on Components of Hematopoietic Stem Cells Collected from Healthy Donors]

Authors :
Chun-Hong, Sun
Jian-Na, Yao
Fang, Liu
Xiao-Juan, Wang
Juan-Juan, Ma
Mi-Mi, Cui
Mei, Zhang
Xiao-Ning, Wang
Source :
Zhongguo shi yan xue ye xue za zhi. 24(6)
Publication Year :
2016

Abstract

To investigate the effects of different hemapheresis procedures on the components of hematopoietic stem cells(HSCs) collected from helathy donors.twelve donors were underwent stem cell collection from January 2015 to August 2016, and the stem cells were randomly colleted by AutoPBSC procedure of COBE spectra and MNC procedure of the Spectra Optia blood cell separator, the mononuclear cells, CD34The circulating blood volume, the acquisition time and dosage of anticoagulants were not significantly different between two procedures. The volume and the mononuclear cell count collected by AutoPBSC procedure were lower than those by the MNC procedure, while the CD34Compared with MNC procedure of the Spectra Optia blood cell separator, the number of collected stem cells, lymphocytes and platelets are higher by using AutoPBSC procedure of the COBE spectra blood cell separator.

Details

ISSN :
10092137
Volume :
24
Issue :
6
Database :
OpenAIRE
Journal :
Zhongguo shi yan xue ye xue za zhi
Accession number :
edsair.pmid..........60b50ff6c0de183e0e907b17530073ed