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New Oxazolo[5,4
- Source :
- International journal of molecular sciences. 23(19)
- Publication Year :
- 2022
-
Abstract
- Cancer is a large group of diseases in which the rapid proliferation of abnormal cells generally leads to metastasis to surrounding tissues or more distant ones through the lymphatic and blood vessels, making it the second leading cause of death worldwide. The main challenge in designing a modern anticancer therapy is to develop selective compounds that exploit specific molecular targets. In this work, novel oxazolo[5,4
- Subjects :
- Vascular Endothelial Growth Factor A
ATP Binding Cassette Transporter, Subfamily B
Dose-Response Relationship, Drug
Molecular Structure
Antineoplastic Agents
Isoxazoles
Adenocarcinoma
Vascular Endothelial Growth Factor Receptor-2
Molecular Docking Simulation
Structure-Activity Relationship
Pyrimidines
Purines
Colonic Neoplasms
Humans
Fluorouracil
Cisplatin
Drug Screening Assays, Antitumor
Cell Proliferation
Subjects
Details
- ISSN :
- 14220067
- Volume :
- 23
- Issue :
- 19
- Database :
- OpenAIRE
- Journal :
- International journal of molecular sciences
- Accession number :
- edsair.pmid..........5de3dea76b7ec8d825b7165387ead37a