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Apparatus to investigate the insulation impedance and accelerated life-testing of neural interfaces
- Source :
- Journal of Neural Engineering
- Publication Year :
- 2018
- Publisher :
- IOP Publishing, 2018.
-
Abstract
- Objective. Neural interfaces and other implantable micro-devices that use polymer-encapsulated integrated circuits will only be allowed in medical devices when their lifetimes can be estimated from experimental data. An apparatus has been developed and tested that allows hundreds of insulated samples (interdigitated combs) to be aged under accelerated conditions of high temperature and voltage stress. Occasionally, aging is paused while the sample’s impedance is measured; the impedance spectrogram may show degradation as it progresses before failure. Approach. The design was based on practical considerations which are reviewed. A Solartron Modulab provides the frequency response analyser and the femtoammeter. The apparatus can accommodate batches of samples at several temperatures and with different aging voltage waveforms. It is important to understand features of the spectra that are not due to comb–comb leakage, but come from other places (for example substrate-solution leakage); some have been observed and investigated using SPICE. Main results. The design is described in detail and test results show that it is capable of making measurements over long periods, at least up to 67 °C. Despite the size of the apparatus, background capacitance is about 1 pF and comb–comb capacitances of about 30 pF can be measured down to 10 mHz, an impedance of about 100 GΩ. An important discovery was the advantage of grounding the bathing solution, primarily in that it raises the measurement ceiling. Observation and SPICE simulation shows that leakage from the substrate to the bathing solution can give phase lags >90°, in contrast to comb–comb leakage which reduces phase lag to
- Subjects :
- Paper
impedance spectroscopy
apparatus
integrated circuit
Temperature
Wavelet Analysis
life-testing
Electrodes, Implanted
Equipment Failure Analysis
accelerated tests
electrochemical impedance spectroscopy
Coated Materials, Biocompatible
Electric Impedance
encapsulation
Humans
Computer Simulation
Equipment Failure
Microelectrodes
Subjects
Details
- Language :
- English
- ISSN :
- 17412552 and 17412560
- Volume :
- 15
- Issue :
- 6
- Database :
- OpenAIRE
- Journal :
- Journal of Neural Engineering
- Accession number :
- edsair.pmid..........5dcf8dd1962286ac2a790b0d436f9e28