[Studies on the changes of chemical constituent in Inula nervosa during the processing]

To research the changes of chemical constituent in Inula nervosa during the processing.Inula nervosa processed with different conditions was determined by HPLC,with acetonitrile--water as a mobile phase using gradient elution, and the detective wavelength was 280 nm. The emerging compounds 1 was extracted by 50% ethanol, isolated and purified using chromatography, and identified according to the physicochemical properties and spectral analysis.The HPLC chromatogram of lnula nervosa changes before and after processing. A monomer compounds was isolated from processed Inula nervosa. It was Identified as 5-hydroxymethylfurfural.The chemical constituent of Inula nervosa changes during the processing. It is the first time that compound 1 were isolated from Inula.