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[TTF-1: neither angel nor demon]

Authors :
Marie, Gilbert-Sirieix
Liliane, Massaad-Massade
Source :
Medecine sciences : M/S. 27(2)
Publication Year :
2011

Abstract

Expressed in thyroid, lung and diencephalon, the Thyroid transcription factor-1 (TTF-1) regulates, in these organs, the transcription of specific genes. This review focuses on the use of TTF-1 as a diagnostic tool in thyroid and lung carcinomas. According to the literature, TTF-1 seems to be involved in aggressive relapses. In some cases it could be also involved in the remission. The use of TTF-1 as a prognostic tool for some neoplasms is discussed.

Details

Language :
French
ISSN :
07670974
Volume :
27
Issue :
2
Database :
OpenAIRE
Journal :
Medecine sciences : M/S
Accession number :
edsair.pmid..........5b5ad01e2d3b61cd92c1f984c1f2428b