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Arterial inflammation measured by

Authors :
Ryota, Iwatsuka
Yuya, Matsue
Taishi, Yonetsu
Toshihiro, O'uchi
Akihiko, Matsumura
Yuji, Hashimoto
Kenzo, Hirao
Source :
Atherosclerosis. 268
Publication Year :
2017

Abstract

AlthoughWe retrospectively utilized the records of 309 subjects aged over 65 years, without a history of coronary artery disease, who underwentDuring a median follow-up of 3.9 years, 28 subjects experienced CHD events and 12 patients died due to non-CHD causes. The highest TBR tertile was associated with a high CHD event rate, accounting for death due to non-CHD causes as a competing risk (Gray test, p = 0.005). In a Fine and Gray competing risk proportional hazard regression model, TBR was associated with significantly high CHD events independently of FRS, with a hazard ratio (HR) of 1.19 per 0.1 TBR increase (p 0.001). Likewise, a significant increase in the area under the curve (from 0.57 to 0.73, p = 0.028) and a significant improvement in net reclassification (0.42, p = 0.038) were observed when TBR was added to the model with FRS alone.In older subjects with no history of malignant disease or overt coronary artery disease, arterial inflammation evaluated by FDG uptake provides information on future occurrence of coronary artery events.

Details

ISSN :
18791484
Volume :
268
Database :
OpenAIRE
Journal :
Atherosclerosis
Accession number :
edsair.pmid..........594d3c9161e7cc04e4d03dcb1faec34e