Using DNA sequencing data to quantify T cell fraction and therapy response

Authors :: Robert, Bentham
Kevin, Litchfield
Thomas B K, Watkins
Emilia L, Lim
Rachel, Rosenthal
Carlos, Martínez-Ruiz
Crispin T, Hiley
Maise Al, Bakir
Roberto, Salgado
David A, Moore
Mariam, Jamal-Hanjani
Charles, Swanton
Gareth A, Wilson
Source :: Nature. 597(7877)
Publication Year :: 2020
Abstract: The immune microenvironment influences tumour evolution and can be both prognostic and predict response to immunotherapy

Subjects :: Male
Receptors, Antigen, T-Cell, alpha-beta
T-Lymphocytes
Adenocarcinoma of Lung
Prognosis
Cohort Studies
Lymphocytes, Tumor-Infiltrating
Neoplasms
Mutation
Exome Sequencing
Aspartic Acid Endopeptidases
Humans
Exome
Female
Immunotherapy

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