Effect of herbicides on human skin. Penetration of herbicides through the epidermis 'in vitro'

Penetration of herbicides GRAMOXONE and REGLONE through human epidermis was studied "in vitro". A special diffusion equipment was used and the method of Calderbank and Yuen was modified for quantitative determination of efficient components (paraquat, diquat) of both herbicides. Penetration of the chosen herbicides was different and surfactants contained in herbicides were found to play a role in penetration into the skin.