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[Epidemic keratoconjunctivitis: treatment results during an epidemic]
- Source :
- Klinische Monatsblatter fur Augenheilkunde. 197(3)
- Publication Year :
- 1990
-
Abstract
- 150 patients with adenovirus type 8 infection where treated at random, in a prospective study. Based upon a quantifiable conjunctivitis severity score we tried to find out where there are differences in treatment. The best results were seen using polyvinylpyrrolidone-iodine (Betaisodona) although it could not prevent totally subepithelial corneal infiltrates. The combination of exogenous interferon alpha with polyvinylpyrrolidone-iodo-drops or trifluorothymidine-drops was less successful. We could not show any prophylactic effect of interferon on uninflamed fellow eyes. Treatment with vasoconstrictor did not show any therapeutic or prophylactic potency. This group of patients must be seen as a control group and the results of effective therapy should significantly differ from the results in this group. Topical corticosteroids should be reserved for severe symptomatic cases and those with iritis and pseudomembranous conjunctivitis. Giving topical corticosteroids in combination with antibiotics we did not find any influence on the incidence of subepithelial keratitis or the number of corneal infiltrates. The mean duration of acute keratoconjunctivitis using this therapy was longer than the mean duration in the control group with vasoconstrictor.
- Subjects :
- Adult
Aged, 80 and over
Adolescent
Oxymetazoline
Acrylic Resins
Keratoconjunctivitis
Eye Infections, Viral
Middle Aged
Dexamethasone
Disease Outbreaks
Trifluridine
Adenovirus Infections, Human
Child, Preschool
Humans
Drug Therapy, Combination
Interferons
Prospective Studies
Gentamicins
Ophthalmic Solutions
Child
Povidone-Iodine
Aged
Subjects
Details
- Language :
- German
- ISSN :
- 00232165
- Volume :
- 197
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Klinische Monatsblatter fur Augenheilkunde
- Accession number :
- edsair.pmid..........5189fab5ab63e01c49ea437909ac73c5