Purinergic receptor Y

Authors :: Julian, Merz
Philipp, Albrecht
Sunaina, von Garlen
Ibrahim, Ahmed
Daniel, Dimanski
Dennis, Wolf
Ingo, Hilgendorf
Carmen, Härdtner
Katja, Grotius
Florian, Willecke
Timo, Heidt
Heiko, Bugger
Natalie, Hoppe
Ulrich, Kintscher
Constantin, von Zur Mühlen
Marco, Idzko
Christoph, Bode
Andreas, Zirlik
Peter, Stachon
Source :: Basic research in cardiology. 113(6)
Publication Year :: 2018
Abstract: Sterile inflammation of visceral fat, provoked by dying adipocytes, links the metabolic syndrome to cardiovascular disease. Danger-associated molecular patterns, such as adenosine triphosphate (ATP), are released by activated or dying cells and orchestrate leukocyte infiltration and inflammation via the purinergic receptor P2Y