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Authors :
Falguni S, Vyas
Carl P, Nelson
Fiona, Freeman
David J, Boocock
Alan J, Hargreaves
John M, Dickenson
Source :
European journal of pharmacology. 813
Publication Year :
2017

Abstract

Tissue transglutaminase 2 (TG2) is modulated by protein kinase A (PKA) mediated phosphorylation: however, the precise mechanism(s) of its modulation by G-protein coupled receptors coupled to PKA activation are not fully understood. In the current study we investigated the potential regulation of TG2 activity by the β

Subjects

Subjects :
Transglutaminases
Cyclic AMP-Dependent Protein Kinases
Cell Line
Rats
Enzyme Activation
Catecholamines
GTP-Binding Proteins
Animals
Calcium
Myocytes, Cardiac
Protein Glutamine gamma Glutamyltransferase 2
Receptors, Adrenergic, beta-2
Enzyme Inhibitors
Phosphorylation
Signal Transduction

Details

ISSN :
18790712
Volume :
813
Database :
OpenAIRE
Journal :
European journal of pharmacology
Accession number :
edsair.pmid..........4a5d398c18fb5574dc22ad3e7a41ffdf

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Authors Abstract Subjects Details