Efficacy and Safety of Turmeric Extracts for the Treatment of Knee Osteoarthritis: a Systematic Review and Meta-analysis of Randomised Controlled Trials

Authors :: Zhiqiang, Wang
Ambrish, Singh
Graeme, Jones
Tania, Winzenberg
Changhai, Ding
Arvind, Chopra
Siddharth, Das
Debashish, Danda
Laura, Laslett
Benny, Antony
Source :: Current rheumatology reportsPapers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance. 23(2)
Publication Year :: 2020
Abstract: Finding appropriate pharmacological options to treat osteoarthritis (OA) remain challenging. We aimed to determine the efficacy and safety of all types of turmeric extracts for the management of knee OA.Sixteen RCTs of up to 16 weeks duration including 1810 adults with knee OA were included. Eleven RCTs compared the efficacy of turmeric extracts with placebo and five with active comparators (NSAIDs). The overall risk bias of included RCTs was moderate. Turmeric extracts significantly reduced knee pain (SMD - 0.82, 95% CI - 1.17 to - 0.47, I

Subjects :: Curcuma
Plant Extracts
Anti-Inflammatory Agents, Non-Steroidal
Humans
Pain
Osteoarthritis, Knee
Randomized Controlled Trials as Topic

ISSN :: 15346307
Volume :: 23
Issue :: 2
Database :: OpenAIRE
Journal :: Current rheumatology reportsPapers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance
Accession number :: edsair.pmid..........49693b3c33836cd6c1bd7d63d057c2ec

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