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Epidemiological data and treatment strategies in children with severe haemophilia in Italy
- Source :
- Annali dell'Istituto superiore di sanita. 56(4)
- Publication Year :
- 2020
-
Abstract
- In a period of important therapeutic changes in the field of haemophilia care, we provide updated statistics on children with severe haemophilia (0-12 years of age) in Italy.Data presented are from the Italian National Registry of Congenital Coagulopathies (NRCC) - survey 2017.Children with severe Haemophilia A (HA) were 242, those with severe haemophilia B (HB) 48. Prophylaxis was adopted in 92.1% of individuals with severe HA and 88.6% with severe HB. Thirty-nine children (14.8%) were on treatment for inhibitors. FVIII prescribed to children with severe HA represented 11.1% of the total consumption, of which 4.6% was extended half-life (EHL). FIX given to children with HB accounted for 7.2% of the total FIX, of which 19.1% was EHL-FIX.The paediatric population analysed is characterized by a great adherence to therapy, so this data may constitute a benchmark for use of new, alternative therapies in the coming years.
Details
- ISSN :
- 23848553
- Volume :
- 56
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- Annali dell'Istituto superiore di sanita
- Accession number :
- edsair.pmid..........43859f626f2cc419286e466709e759cf