Cytotoxicity of AMANTADIG - a semisynthetic digitoxigenin derivative - alone and in combination with docetaxel in human hormone-refractory prostate cancer cells and its effect on Na

Authors :: Izabella Thaís, Silva
Jennifer, Munkert
Elke, Nolte
Naira Fernanda Zanchett, Schneider
Sayonarah Carvalho, Rocha
Ana Carolina Pacheco, Ramos
Wolfgang, Kreis
Fernão Castro, Braga
Rodrigo Maia, de Pádua
Alex G, Taranto
Vanessa, Cortes
Leandro Augusto, Barbosa
Sven, Wach
Helge, Taubert
Cláudia Maria Oliveira, Simões
Source :: Biomedicinepharmacotherapy = Biomedecinepharmacotherapie. 107
Publication Year :: 2018
Abstract: Cardiac glycosides (CGs) are natural compounds used to treat congestive heart failure. They have garnered attention as a potential cancer treatment option, especially because they bind to Na

Subjects :: Male
Cell Survival
Survivin
Cell Cycle
Prostatic Neoplasms
Apoptosis
Drug Synergism
Docetaxel
Gene Expression Regulation, Neoplastic
Molecular Docking Simulation
Necrosis
Cell Line, Tumor
Humans
RNA, Messenger
Sodium-Potassium-Exchanging ATPase
Digitoxigenin
Cell Proliferation

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