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Melanoma Differentiation Trajectories Determine Sensitivity toward Pre-Existing CD8

Authors :
Franziska Noelle, Harbers
Beatrice, Thier
Simone, Stupia
Si, Zhu
Marion, Schwamborn
Vicky, Peller
Heike, Chauvistré
Pietro, Crivello
Katharina, Fleischhauer
Alexander, Roesch
Antje, Sucker
Dirk, Schadendorf
Yong, Chen
Annette, Paschen
Fang, Zhao
Source :
The Journal of investigative dermatology. 141(10)
Publication Year :
2020

Abstract

The highly plastic nature of melanoma enables its transition among diverse cell states to survive hostile conditions. However, the interplay between specific tumor cell states and intratumoral T cells remains poorly defined. With MAPK inhibitor‒treated BRAF

Details

ISSN :
15231747
Volume :
141
Issue :
10
Database :
OpenAIRE
Journal :
The Journal of investigative dermatology
Accession number :
edsair.pmid..........3cb49ed66524fbce117ded762ec6a459