Back to Search
Start Over
[Pulmonary aspergillosis in a child with chronic granulomatous disease]
- Source :
- La Tunisie medicale. 81(10)
- Publication Year :
- 2007
-
Abstract
- The chronic granulomatous disease is characterised by the occurence of multiple bacterial and fungal infections since the early childhood. This susceptibility to infections must be prevented by a primary prophlylaxis against the opportunistic germs like pneumocystis and aspergillus. Our case is about a twelve-year-old boy who had a prophylaxis since his fourth month of life. At 10 years he presented a pleuro-pneumonia refractory to a large spectrum antibiotherapy. The aspergillar etiology was established on clinical, radiological and serological arguments. An amphotericine B treatment allowed a good clinical and radiological outcome of this pleuro-pulmonary affection. However, a dorsal spondylodiscitis complicated the course of the disease. A secondary vertebral aspergillosis or a Pott's disease were suspected. The vertebral bipsy was'nt conclusive. The association of antituberculous and antifungal agents with adjuvant molecules (IFN, granulotic transfusions and GM-CSF) permitted a good clinical outcome and the stabilisation of the radiological lesions.
- Subjects :
- Male
Lung Diseases, Fungal
Aspergillosis
Humans
Child
Granulomatous Disease, Chronic
Subjects
Details
- Language :
- French
- ISSN :
- 00414131
- Volume :
- 81
- Issue :
- 10
- Database :
- OpenAIRE
- Journal :
- La Tunisie medicale
- Accession number :
- edsair.pmid..........3a3cfe3b4199b286bd11231653d5c78e