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[Effect of electroacupuncture on expression of stromal cell derived factor-1α in focal ischemic cerebral tissue of rats with cerebral ischemia/ reperfusion injury]

Authors :
Wei-Kai, Zhu
Hui, Shen
Peng-Xin, Zhang
Lin, Zhong
Yan-Yan, Zhao
Cheng-Ming, Wang
Nan, Wang
Source :
Zhen ci yan jiu = Acupuncture research. 44(9)
Publication Year :
2019

Abstract

To observe the effect of electroacupuncture (EA) of "Baihui" (GV20) and "Zusanli" (ST36) on the expression of stromal cell derived factor-1α (SDF-1α) and CD34 in ischemic cortex tissue of cerebral ische-mia /reperfusion injury (CI/RI) rats, so as to study its mechanisms underlying improving CI/RI.Thirty male SD rats were equally and randomly divided into sham operation, model and EA groups (After modeling, the neurological deficit score, and the numbers of SDF-1α and CD34-positive cells in the ischemic cerebral cortex tissue were significantly increased in the model group (EA of GV20 and ST36 can improve neurological function of CI/RI rats, which may be associated with its effect in up-regulating the expression of SDF-1α and CD34 proteins in the ischemic cerebral cortex tissues.

Details

ISSN :
10000607
Volume :
44
Issue :
9
Database :
OpenAIRE
Journal :
Zhen ci yan jiu = Acupuncture research
Accession number :
edsair.pmid..........351a91e14d0cd5cd87f77669c1029df3