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Low-dose Aspirin prevents hypertension and cardiac fibrosis when thromboxane A
- Source :
- Pharmacological research. 170
- Publication Year :
- 2021
-
Abstract
- Enhanced platelet activation has been reported in patients with essential hypertension and heart failure. The possible contribution of platelet-derived thromboxane (TX)A
- Subjects :
- Adult
Blood Platelets
Male
Receptors, Thromboxane
Blood Pressure
Receptors, Epoprostenol
Thromboxane A2
Animals
Humans
Myocytes, Cardiac
Myofibroblasts
Antihypertensive Agents
Cells, Cultured
Mice, Knockout
Aspirin
Middle Aged
Fibrosis
Mice, Inbred C57BL
Disease Models, Animal
Case-Control Studies
Female
Antifibrotic Agents
Essential Hypertension
Cardiomyopathies
Biomarkers
Platelet Aggregation Inhibitors
Subjects
Details
- ISSN :
- 10961186
- Volume :
- 170
- Database :
- OpenAIRE
- Journal :
- Pharmacological research
- Accession number :
- edsair.pmid..........3437bcc5e5666700e3a0fcba4fb6694a