[Acute mucosal damage of the stomach of the Wistar rat and its prevention with the drug combination droperidol/atropine--an animal experiment study]

Authors :: P M, Weber
H, Schramm
Source :: Zeitschrift fur experimentelle Chirurgie, Transplantation, und kunstliche Organe : Organ der Sektion Experimentelle Chirurgie der Gesellschaft fur Chirurgie der DDR. 18(3)
Publication Year :: 1985
Abstract: The employment of the alpha receptor blocking Droperidol with and without combination of atropine for prophylaxis of the acute mucosal damage of the stomach was investigated in the experimental animal Wistar rat. The immobilisation stress in the stress roll was chosen as stress model. The animals get an infusion programme by a central venous catheter. The stomachs were searched for macroscopic mucosal changes after an immobilisation period of 6 hours. The results were certained statistically. The acute mucosal damage in the rat stomach could be prevented in 100% (p 0.05) by means of the drug combination Droperidol/atropine (IV).

Subjects :: Atropine
Gastric Mucosa
Stress, Physiological
Animals
Droperidol
Drug Therapy, Combination
Female
Rats, Inbred Strains
Stomach Ulcer
Rats

Language :: German
ISSN :: 02327295
Volume :: 18
Issue :: 3
Database :: OpenAIRE
Journal :: Zeitschrift fur experimentelle Chirurgie, Transplantation, und kunstliche Organe : Organ der Sektion Experimentelle Chirurgie der Gesellschaft fur Chirurgie der DDR
Accession number :: edsair.pmid..........330dea5b4166280a96c5c2cb6926c49f

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