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NH-sulfoximine: A novel pharmacological inhibitor of the mitochondrial F
- Source :
- British journal of pharmacology. 178(2)
- Publication Year :
- 2019
-
Abstract
- The mitochondrial FThe chemical structure of the FNHS selectively blocks the consumption of ATP by mitochondria leading a subtle cytotoxicity associated via the concomitant engagement of autophagy which impairs cell viability. NHS achieves such a function independently of the FThe novel sulfoximine analogue of BTB-06584, NHS, acts as a selective pharmacological inhibitor of the mitochondrial F
Details
- ISSN :
- 14765381
- Volume :
- 178
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- British journal of pharmacology
- Accession number :
- edsair.pmid..........301f0774a06b54fa5bb1a3056fe01950