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Clinical efficacy of atezolizumab plus bevacizumab and chemotherapy in

Authors :
Howard Jack, West
Mark, McCleland
Federico, Cappuzzo
Martin, Reck
Tony Sk, Mok
Robert M, Jotte
Makoto, Nishio
Eugene, Kim
Stefanie, Morris
Wei, Zou
David, Shames
Meghna, Das Thakur
Geetha, Shankar
Mark A, Socinski
Source :
Journal for immunotherapy of cancer. 10(2)
Publication Year :
2021

Abstract

The efficacy of atezolizumab (A) and/or bevacizumab (B) with carboplatin/paclitaxel (CP) chemotherapy was explored in the phase III, randomized IMpower150 study in patients with non-squamous non-small cell lung cancer (NSCLC) according toMutation status was determined by circulating tumor DNA next-generation sequencing. Overall survival (OS) and progression-free survival (PFS) were analyzed in a mutation-evaluable intention-to-treat population (MEP; n=920) and SP263 (programmed cell death ligand 1 (PD-L1)) biomarker-evaluable population (n=774).Within the mThese analyses support previous findings of mutation of

Details

ISSN :
20511426
Volume :
10
Issue :
2
Database :
OpenAIRE
Journal :
Journal for immunotherapy of cancer
Accession number :
edsair.pmid..........2ede524549d5f67235e2fbf42af15aa3