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[Research progress on the mechanism of protease-activated receptor 2 in colorectal cancer]
- Source :
- Zhonghua bing li xue za zhi = Chinese journal of pathology. 50(9)
- Publication Year :
- 2021
-
Abstract
- 蛋白酶激活受体2（protease activated receptor 2，PAR2）是G蛋白耦联受体超家族的成员，广泛表达于肠上皮细胞中。在结直肠癌的肿瘤微环境中，存在着多种蛋白酶，可以激活肿瘤细胞或间质细胞中的PAR2，从而调控肿瘤细胞的行为。在本综述中，作者关注于PAR2在结直肠癌发生发展过程中调控的信号通路，对PAR2的作用机制展开阐述。.
- Subjects :
- Humans
Receptor, PAR-2
Colorectal Neoplasms
Subjects
Details
- ISSN :
- 05295807
- Volume :
- 50
- Issue :
- 9
- Database :
- OpenAIRE
- Journal :
- Zhonghua bing li xue za zhi = Chinese journal of pathology
- Accession number :
- edsair.pmid..........2cfaeb92f483a1eb73180c982c359944