Prognostic Value of Resistive Index in Neonates with Hypoxic Ischemic Encephalopathy

To evaluate the role of Resistive index measured by cranial doppler ultrasonography in predicting the risk of death/ abnormal neurodevelopmental outcomes in term neonates with hypoxic ischemic encephalopathy.We enrolled 50 term asphyxiated neonates with hypoxic ischemic encephalopathy and measured resistive index within 72 hours from the anterior cerebral artery. Participants underwent tone and developmental assessment at 6-12 months.Among the 50 neonates, 25 (50%) had abnormal resistive index (0.56 or0.80). Presence of abnormal resistive index increased the risk of death/ abnormal neurological outcomes at 6-12 months [RR (95% CI): 7.5 (2.0,8.6), P0.01].An abnormal resistive index is associated with death/ neurodevelopmental impairment in neonatal hypoxic ischemic encephalopathy.