Prolonged activation of nasal immune cell populations and development of tissue-resident SARS-CoV-2-specific CD8

Authors :: Anna H E, Roukens
Cilia R, Pothast
Marion, König
Wesley, Huisman
Tim, Dalebout
Tamar, Tak
Shohreh, Azimi
Yvonne, Kruize
Renate S, Hagedoorn
Mihaela, Zlei
Frank J T, Staal
Fenna J, de Bie
Jacques J M, van Dongen
Sesmu M, Arbous
Jaimie L H, Zhang
Maaike, Verheij
Corine, Prins
Anne M, van der Does
Pieter S, Hiemstra
Jutte J C, de Vries
Jacqueline J, Janse
Meta, Roestenberg
Sebenzile K, Myeni
Marjolein, Kikkert
Maria, Yazdanbakhsh
Mirjam H M, Heemskerk
Hermelijn H, Smits
Simon P, Jochems
Frits, Rosendaal
Source :: Nature immunology. 23(1)
Publication Year :: 2021
Abstract: Systemic immune cell dynamics during coronavirus disease 2019 (COVID-19) are extensively documented, but these are less well studied in the (upper) respiratory tract, where severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replicates

Subjects :: CD4-Positive T-Lymphocytes
Neutrophils
SARS-CoV-2
COVID-19
HLA-DR Antigens
Respiratory Mucosa
CD8-Positive T-Lymphocytes
Nose
Antibodies, Viral
Monocytes
Killer Cells, Natural
Memory T Cells
Nasopharynx
Humans
Prospective Studies
Granulocytes

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