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Diagnostic and Dosimetry Features of [
- Source :
- Molecular imaging and biologyReferences.
- Publication Year :
- 2022
-
Abstract
- Paediatric diffuse high-grade gliomas (PDHGG) are rare central nervous system neoplasms lacking effective therapeutic options. Molecular imaging of tumour metabolism might identify novel diagnostic/therapeutic targets. In this study, we evaluated the distribution and the dosimetry aspects of [Paediatric patients with PDHGG were prospectively recruited. [Ten patients were enrolled (median age 9, range 6-16 years, 6 females). Diagnoses were diffuse midline gliomas (n = 8, 5 of which with H3K27 alterations) and diffuse hemispheric gliomas (n = 2). Six patients had visible tracer uptake (SUV: 1.0 ± 0.6 TBR: 5 ± 3.1). [[
Details
- ISSN :
- 18602002
- Database :
- OpenAIRE
- Journal :
- Molecular imaging and biologyReferences
- Accession number :
- edsair.pmid..........2519315c9c4c1c79994c71231b1c6450