Demonstration of the diagnostic agreement of capillary and venous blood samples, using hepatitis-C virus SD Bioline

Simplifying hepatitis C virus (HCV) screening is a key step in achieving the elimination of HCV as a global public health threat by 2030.The objective of this study was to demonstrate the agreement of capillary blood and venipuncture specimens when using SD BiolineRecruitment was conducted prospectively among adult patients presenting for HCV testing at the Médecins Sans Frontières (MSF) clinic of Preah Kossamak Hospital (Phnom Penh, Cambodia) between October and November 2017. Capillary and venous blood samples were collected from consenting patients and tested with SD BiolineAmong 421 pairs of samples collected, reader disagreement occurred for 0.7% (n = 3) of the participants. Sixty-four percent of capillary and venous blood sample pairs tested positive for HCV, with a Kappa statistic of 0.985 between the two methods. Three participants with discrepant sample pair results tested positive with EIA.Capillary and venous blood samples were concordant when tested with HCV SD Bioline