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Improvement in ocular symptoms and signs in patients with

Authors :
Riadh, Messaoud
Lamia, El Fekih
Anis, Mahmoud
Hager, Ben Amor
Radhouane, Bannour
Serge, Doan
Moncef, Khairallah
Source :
Clinical Ophthalmology (Auckland, N.Z.)
Publication Year :
2018

Abstract

Purpose: To evaluate the clinical improvement in ocular symptoms and signs in patients suffering from Demodex anterior blepharitis after using a novel cleansing wipe impregnated with 2.5% terpinen-4-ol and 0.2% hyaluronic acid. Study design: This was an exploratory, multicenter, open, randomized, two-parallel group comparative study. Methods: Forty-eight patients with Demodex anterior blepharitis were randomly assigned to apply the sterile wipe T1172 (Blephademodex®), either once daily (n=24, Group 1) or twice daily (n=24, Group 2) for 29 days. Overall ocular discomfort and other individual symptoms were measured using a 0–10 numeric rating scale at Day 8 and Day 29. Ocular signs, including eyelid margin hyperemia and number of cylindrical dandruff, were examined at slit lamp. Overall treatment performance by investigator, patient satisfaction and tolerance were evaluated with questionnaires. Results: Overall ocular discomfort was significantly reduced from baseline (p

Details

ISSN :
11775467
Volume :
13
Database :
OpenAIRE
Journal :
Clinical ophthalmology (Auckland, N.Z.)
Accession number :
edsair.pmid..........1d637cff5035963fff0d5687ef788238