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Zinc-catalyzed C-H alkenylation of quinoline
- Source :
- Chemical communications (Cambridge, England). 57(40)
- Publication Year :
- 2021
-
Abstract
- A zinc-catalyzed C-H alkenylation of quinoline N-oxides with ynones has been developed to rapidly assemble a broad collection of valuable quinoline-enol organic architectures. Uncommonly, this novel reaction involves C-H functionalization, and N-O, C-C and C[triple bond, length as m-dash]C bond cleavage in one operation, and leads exclusively to the formation of an enol rather than a keto product. Application of the enols generated was highlighted by further derivative transformation and preparation of a series of "BODIPY" analogues with high quantum yields (up to 86%).
Details
- ISSN :
- 1364548X
- Volume :
- 57
- Issue :
- 40
- Database :
- OpenAIRE
- Journal :
- Chemical communications (Cambridge, England)
- Accession number :
- edsair.pmid..........180fdbd3e06973e9b43f93ac15573224