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[L-carnitine: safe and effective for asthenozoospermia]
- Source :
- Zhonghua nan ke xue = National journal of andrology. 16(5)
- Publication Year :
- 2010
-
Abstract
- One of the important reasons for male infertility is asthenozoospermia, for which there is no specific cure for the time being. The authors explored the clinical effect of L-carnitine for infertile males with asthenozoospermia.A total of 135 patients with asthenozoospermia were randomly divided into Groups A (n = 68) and B (n = 67), the former treated with L-carnitine (2 g/d) and vitamin E, while the latter with vitamin E only, both for 3 months. All the patients received semen analyses before and after the treatment, and were observed for adverse effects. The pregnancy rates of their wives were recorded.Group A showed a significantly increased percentage of forward motile sperm after the treatment (45.4% +/- 11.1%) as compared with pretreatment (28.6% +/- 9.2%) (P0.01), but no statistically significant differences were found in sperm density and the percentage of the sperm of normal morphology (P0.05). The rate of pregnancy was significantly higher in Group A (31.1%) than in B (3.8%) after the treatment (P0.01). No adverse events were found during the treatment.L-carnitine, capable of significantly improving sperm motility and raising the rate of pregnancy, is a safe and effective therapeutic option for asthenozoospermia.
Details
- ISSN :
- 10093591
- Volume :
- 16
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Zhonghua nan ke xue = National journal of andrology
- Accession number :
- edsair.pmid..........15ec821e29a544767f896ac2dbb2aa5d