Intracellular survival of

Authors :: Tinashe K, Nyazika
Lusako, Sibale
Joseph, Phiri
Megan, De Ste Croix
Zydrune, Jasiunaite
Christopher, Mkandawire
Rose, Malamba
Anstead, Kankwatira
Miriam, Manduwa
Daniela M, Ferreira
Tonney S, Nyirenda
Marco R, Oggioni
Henry C, Mwandumba
Kondwani C, Jambo
Source :: Frontiers in immunology. 13
Publication Year :: 2022
Abstract: People Living with HIV (PLHIV) are at an increased risk of pneumococcal pneumonia than HIV-uninfected adults, but the reasons for this are still not well understood. We investigated whether alveolar macrophages (AM) mediated control of pneumococcal infection is impaired in PLHIV compared to HIV-uninfected adults. We assessed anti-bactericidal activity against