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[Galenic quality of test substances]

Authors :
M, Puschmann
Source :
Zeitschrift fur Hautkrankheiten. 62(24)
Publication Year :
1987

Abstract

According to experimental investigations (microscopy, analytical determination, method of agar diffusion, spreading on human skin) there is no inhomogeneity detectable among the 20 test substances of the Standard-Epicutantest-HERMAL. The following criteria are proved: equal spectrum of the grain sizes, equivalent contents of the active substance along the whole syringe, good release of the active substances from vaseline, homogeneous spreading of the active substances in the syringe, homogeneous spreading on human skin, when Finn Chambers on Scanpor (FCS) and Epiquick plasters are applied. These findings meet the requirements for relevant and reproducible test results.

Details

Language :
German
ISSN :
03010481
Volume :
62
Issue :
24
Database :
OpenAIRE
Journal :
Zeitschrift fur Hautkrankheiten
Accession number :
edsair.pmid..........129d3ba0cfb52a3981203dd2db53ec9b