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Inhibition of WEE1 Is Effective in
- Source :
- Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 39(33)
- Publication Year :
- 2021
-
Abstract
- Outcomes inPatients with newly diagnosed mCRC were registered into FOCUS4 and tested forFOCUS4-C was conducted between April 2017 and Mar 2020 during which time 718 patients were registered; 247 (34%) wereIn this phase II randomized trial, adavosertib improved PFS compared with AM and demonstrates potential as a well-tolerated therapy for
- Subjects :
- Male
Cell Cycle Proteins
Pyrimidinones
Middle Aged
Protein-Tyrosine Kinases
Prognosis
Survival Rate
Antineoplastic Combined Chemotherapy Protocols
Mutation
Quality of Life
ras Proteins
Humans
Pyrazoles
Female
Enzyme Inhibitors
Neoplasm Metastasis
Tumor Suppressor Protein p53
Colorectal Neoplasms
Watchful Waiting
Follow-Up Studies
Subjects
Details
- ISSN :
- 15277755
- Volume :
- 39
- Issue :
- 33
- Database :
- OpenAIRE
- Journal :
- Journal of clinical oncology : official journal of the American Society of Clinical Oncology
- Accession number :
- edsair.pmid..........0fbc8e57d310ea2157e506e12303c932