Back to Search Start Over

Filamentous vibriophage fs2 encoding the rstC gene integrates into the same chromosomal region as the CTX phage [corrected]

Authors :
Dong Tu, Nguyen
Binh Minh, Nguyen
Huy Hoang, Tran
Tuan Cuong, Ngo
Thanh Huong, Le
Hoai Thu, Nguyen
M John, Albert
Mamoru, Iwami
Masahiko, Ehara
Source :
FEMS microbiology letters. 284(2)
Publication Year :
2008

Abstract

The genome of the filamentous phage of Vibrio cholerae fs2 was found to contain rstC and rstB1 (truncated) genes downstream of ORF500. att-fs2-dir and att-fs2-rev sequences homologous to that of att-CTXphi were found between orf500 and rstC of the fs2 genome. This prompted us to search for the integration site of fs2 in the genomes of V. cholerae O1 and O139. The genome of fs2 was found to integrate downstream of attRS of the CTXphi phage, which integrated into chromosome I of V. cholerae O1 and O139. When infected with fs2, a fimbriate strain of V. cholerae O1 appeared to reduce fimbrial production in an adult rabbit ileal loop assay.

Details

ISSN :
03781097
Volume :
284
Issue :
2
Database :
OpenAIRE
Journal :
FEMS microbiology letters
Accession number :
edsair.pmid..........0c3425a03ba7a7ac1613b6bf5351b465