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Rebound Phenomenon after Nirmatrelvir/Ritonavir Treatment of Coronavirus Disease-2019 in High-Risk Persons

Authors :
Nischal, Ranganath
John C, O'Horo
Douglas W, Challener
Sidna M, Tulledge-Scheitel
Marsha L, Pike
R, Michael O'Brien
Raymund R, Razonable
Aditya, Shah
Source :
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
Publication Year :
2022

Abstract

In a cohort of 483 high-risk patients treated with nirmatrelvir/ritonavir for coronavirus disease-2019, two patients (0.4%) required hospitalization by day 30. Four patients (0.8%) experienced rebound of symptoms, which were generally mild, at median of 9 days after treatment, and all resolved without additional COVID-19-directed therapy.

Details

ISSN :
15376591
Database :
OpenAIRE
Journal :
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Accession number :
edsair.pmid..........0bb76889bb877e4eb3b253c8e9c52d85