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[Fetal hemolytic disease in a patient immunized by six antibodies: diagnosis and treatment]
- Source :
- Annali di ostetricia, ginecologia, medicina perinatale. 111(5)
- Publication Year :
- 1990
-
Abstract
- A case of severe haemolytic disease of the fetus due to six rare alloantibodies is described. In a pregnant women at 23 weeks gestation after the finding of a positive indirect Coombs test maternal antibodies have been precisely identified and titrated: anti-I: 1/23, anti-c: 1/64, anti-S: 1/16, anti-Fya: 1/128, anti-M: 1/64, anti-Jka: 1/32000. Fetal blood group, free and red blood cell adherent antibodies have been investigated on fetal blood samples obtained by means of cord centesis. A compatible donor has been found. Severe fetal anemia has been corrected by ultrasound guided intrauterine transfusions (one abdominal and two intravascular transfusions) with positive outcome of the pregnancy.
Details
- ISSN :
- 03000087
- Volume :
- 111
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Annali di ostetricia, ginecologia, medicina perinatale
- Accession number :
- edsair.pmid..........00fe3d173e1350c5dc1871f0e54e5a9b