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Resistance to amprenavir before and after treatment with lopinavir/ritonavir in highly protease inhibitor-experienced HIV patients
- Publication Year :
- 2004
-
Abstract
- Genotypes in nine highly protease inhibitor (PI)experienced patients were studied before and after lopinavir/ritonavir (LPV/r) treatment. Resistance to amprenavir was the rule both before and after LPV/r treatment. Treatment with LPV/r can select for the 50V mutation. In this setting, significant differences in the inference of the amprenavir phenotype from genotype were observed when using different algorithms.
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.od.....10495..f2a05531afe742bcb3f14fb89c6ac11c