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Pathophysiology of leukocyte-tissue interactions
- Publication Year :
- 2006
-
Abstract
- Unlike most somatic cells, leukocytes are constitutively non-adherent. However, adhesive interactions are not only a required step in essentially all effector functions performed by leukocytes, but they also relay increasingly well-defined intracellular signals that affect the leukocyte as well as the surrounding tissues. Dissecting such signals in leukocytes has provided a wealth of information that contributes to our understanding of how adhesion controls higher-order biological responses, ranging from cell migration to proliferation, differentiation and survival.
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.od.....10495..69f0ba2149f14a19d0d2184b7aa18e43