Ocular and cerebral blood flow analysis in cases with retinopathy of prematurity

Purpose: To compare ocular and cerebral blood flow parameters between infants who had retinopathy of prematurity (ROP) with plus disease and infants who did not have any sign of ROP and plus disease. Materials and Methods: A total of 33 cases were studied. Group 1 included 23 infants who had Zon 2 stage 3 ROP with plus disease, group 2 included 10 infants who did not have ROP and/or plus disease. Ophthalmic artery (OA) and median cereabral artery (MCA) were evaluated during measurements. Peak systolic velocity (PSV), end-diastolic velocity (EDV), mean velocity (MV), pulsatility index (PI) and resistivity index (RI) were recorded. Results: Gestational age and birth weight did not significantly differ between the groups (p=0.69, p=0.91, respectively). For OA; PSV, EDV, MV, PI and RI values were 45.35±14.25 cm/s, 7.83±4.14 cm/s, 19.00±4.35 cm/s, 0.64±0.13 and 0.83±0.07 in group 1, 37.40±5.02 cm/s, 9.70±1.49 cm/s, 18.68±3.38 cm/s, 0.48±0.06 and 0.71±0.11 in group 2, respectively. TSH (p=0.034), Pİ (p